Table 1.

SAMMPRIS Risk Factor Targets and their measurement

RISK FACTOR	GOAL	MEASUREMENT
Primary Risk Factors
LDLc	< 70 mg/dL	Central lab- Direct LDL measurement*
Systolic Blood pressure	< 140 mm Hg (< 130 if diabetic)	Using standardized device provided to site
Secondary Risk Factors
Non-HDLc	< 100 mg/dL	Central lab
HbA1c	< 7.0%	Local lab
Smoking	Cessation	Self reported (PACE score**)
Weight Management	For initial BMI of 25 – 27 kg/m2: target BMI < 25 kg/m2 For initial BMI > 27 kg/m2: target 10% weight loss	Weight at each visit Height at baseline
Physical Activity	≥ 30 min of moderate exercise 3 or more times per week	Self reported (PACE score**)

^*measured by homogeneous enzymatic method (www.sekisuidiagnostics.com).

^**Physician-based Assessment and Counseling for Exercise (PACE) questionaire is performed for smoking and exercise.