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Cherenkov emission spectroscopy of tissue oxygenation in vivo. (a) mouse positioned in the target region with the beam profile delineated in red. (b) typical spectra from a mouse pre and post euthanasia. (c) the results from the fitting procedure for both total hemoglobin concentration (left y-axis) and oxygen saturation (right y-axis). The mean of four animals is shown and the error bars indicate the standard deviation of this small population.
