Table 1.
Metabolism and Transport Drug Interaction Database (DIDB) users
| Institution | Group | Examples of database use |
|---|---|---|
| Pharmaceutical industry & CROs | DMPK Clinical pharmacology Clinical | Tool for IVIVE Modelling: to define acceptable input parameters and validate models |
| Helps optimize design of in vitro and in vivo drug interaction studies | ||
| Provides context for results obtained for candidate compounds | ||
| Provides access to labelling of recently marketed drugs | ||
| DIDB as a research tool: publications - Presentations | ||
| Regulatory agencies | Reviewers | Provides context for results submitted for candidate compounds |
| Helps update guidance documents (DDI, pharmacogenetics) | ||
| DIDB as a research tool: publications - presentations | ||
| Academia | Metabolism | Didactic tool |
| Pharmacokinetics | Resource for courses on DDI | |
| Clinical pharmacology | DIDB as a research tool: publications - presentations |
CRO, contract research organisation; DDI, drug-drug interaction; DMPK, drug metabolism and pharmacokinetics.