Intron 4 sequence from the orthologous GH genes of human, five other primates and Bos taurus (cow). The polymorphic nucleotide at +1169 in the human GH1 gene is marked in green. Mismatched positions are highlighted in yellow. GenBank accession nos: Homo sapiens J03071; Pan troglodytes, chimpanzee (AF374232.1); Gorilla gorilla, gorilla (FP245407.5); Nomascus leucogenys, white-cheeked gibbon (AY621637.1); Pygathrix roxellana, Sichuan-snub-nosed monkey (AY621647.1); Macaca mulatta, rhesus macaque (DQ002799.1); Bos taurus, cow (Bos taurus release Btau_4.0). The location of the consensus sequence of the p53-responsive element (RRRCWWGYYY) is shown in red [16].