Table 1.
Human FABP genes, as listed in the Human Gene Nomenclature Committee (HGNC) and Online Mendelian Inheritance in Man (OMIM) databases
Gene | Common name |
Aliases for proteins | Previous symbols |
Localisation | Chromosomal location |
OMIM ID/ HGNC ID |
Number of amino acids |
---|---|---|---|---|---|---|---|
FABP1 | Liver FABP | L-FABP, hepatic FABP, Z protein, heme-binding protein |
Liver, intestine, pancreas, kidney, lung, stomach |
2p11 | 134650/ 3555 |
127 | |
FABP2 | Intestinal FABP |
I-FABP, gut FABP (gFABP) | Intestine, liver | 4q28-q31 | 134640/ 3556 |
132 | |
FABP3 | Heart FABP |
H-FABP, O-FABP, mammary-derived growth inhibitor (MDGI) |
FABP11 | Cardiac and skeletal muscle, brain, kidney, lung, stomach, testis, adrenal gland, mammary gland, placenta, ovary, brown adipose tissue |
1p33-p31 | 134650/ 3557 |
133 |
FABP4 | Adipocyte FABP |
A-FABP, aP2 | Adipocytes, macrophages, dendritic cells, skeletal muscle fibres |
8q21 | 600434/ 3559 |
132 | |
FABP5 | Epidermal FABP |
E-FABP, keratinocyte-type FABP (KFABP), psoriasis-associated-FABP (PA-FABP) |
Skin, tongue, adipocyte, macrophage, dendritic cells, mammary gland, brain, stomach, intestine, kidney, liver, lung, heart, skeletal muscle, testis, retina, lens, spleen, placenta |
8q21.13 | 605168/ 3560 |
135 | |
FABP6 | Ileal FABP | Il-FABP, Ileal lipid-binding protein (ILLBP), intestinal bile acid-binding protein (I-BABP), gastrophin |
Ileum, ovary, adrenal gland, stomach |
5q23-q35 | 600422/ 3561 |
128 | |
FABP7 | Brain FABP | B-FABP, brain lipid-binding protein (BLBP), MRG |
Brain, central nervous system (CNS), glial cell, retina, mammary gland |
6q22-q23 | 602965/ 3562 |
132 | |
FABP8 | Myelin FABP |
M-FABP, peripheral myelin protein 2 (PMP2) |
Peripheral nervous system, Schwann cells |
8q21.3-q22.1 | 170715/ 9117 |
132 | |
FABP9 | Testis FABP | T-FABP, testis lipid-binding protein (TLBP), PERF, PERF 15 |
Testis, salivary gland, mammary gland |
8q21.13 | --/3563 | 132 | |
FABP12 | --- | --- | Retinoblastoma cell,a retina (ganglion and inner nuclear layer cells),b testicular germ cells,b cerebral cortex,b kidney,b epididymisb |
8q21.13 | --/34524 | 140 |
aExpression found in humans, versus brodents