Table 4.

SNPs having significant association with HDL cholesterol in the study population.

Chromosome	Positiona	dbSNP	refLb	altL	refH	altH	Δpc	χ2	p value
16	56729856	rs1800775	392	196	288	322	0.193	46.2	1.1 × 10-11
16	56730908	rs708272	446	234	318	320	0.151	33.5	7.2 × 10-9
16	56730831	rs711752	451	239	314	312	0.165	31.2	2.4 × 10-8
16	56733948	rs11508026	441	227	303	289	0.167	28.6	9.1 × 10-8
16	56739509	rs7205804	436	244	312	318	0.146	28.4	9.7 × 10-8
16	56740998	rs11076175	535	155	563	73	-0.101	28.1	1.2 × 10-7

^a Position on GenBank sequence NC_000016.4.

^b Counts of reference and alternate alleles for low and high HDL cholesterol groups.

^c Allele frequency difference, calculated as ref_L /(ref_L + alt_L) - ref_H /(ref_H + alt_H).

dbSNPs single nucleotide polymorphism database; HDL, high-density lipoprotein.