Table 5.

Genotyping results for 14 CETP gene SNPs in the test and replicate samples.

Positiona	dbSNP	Study samples			Replicate samples			Overall p valueb
		Δp	p value	Odds ratioc	Δp	p value	Odds ratio
56729658	rs4783962	0.060	1.2 × 10-2	1.38	0.100	2.8 × 10-2	1.87	1. 4 × 10-3
56729856	rs1800775	0.193	1.1 × 10-11	2.26	0.104	1.5 × 10-1	1.40	1. 8 × 10-11
56730831	rs711752	0.165	2.4 × 10-8	1.88	0.208	5.0 × 10-4	2.21	5.9 × 10-11
56730908	rs708272	0.151	7.2 × 10-9	1.92	0.202	3.2 × 10-4	2.25	1.2 × 10-11
56733948	rs11508026	0.167	9.0 × 10-8	1.85	0.186	1.9 × 10-3	2.06	7.1 × 10-10
56739509	rs7205804	0.146	9.7 × 10-8	1.82	0.142	5.6 × 10-3	1.89	1.9 × 10-9
56740998	rs11076175	-0.101	1.2 × 10-7	0.45	-0.006	8.9 × 10-1	0.96	1.6 × 10-6
56743996	rs289716	-0.060	1.6 × 10-2	0.75	-0.039	3.9 × 10-1	0.81	1.1 × 10-2
56745805	rs4784744	-0.075	5.0 × 10-3	0.72	-0.157	8.7 × 10-3	0.53	2.4 × 10-4
56750165	rs1800774	0.009	7.5 × 10-1	1.04	0.102	5.8 × 10-2	1.53	2.5 × 10-1
56750712	rs5882	-0.073	4.4 × 10-3	0.72	-0.017	8.0 × 10-1	0.94	7.7 × 10-3
56751939	rs1800777	-0.041	1.1 × 10-3	0.33	-0.009	2.9 × 10-1	1.06	4.2 × 10-3
56752282	rs1801706	0.029	2.0 × 10-1	1.20	-0.022	2.9 × 10-1	0.73	5.0 × 10-1
56752382	rs289742	-0.023	1.2 × 10-1	0.76	-0.053	4.6 × 10-2	0.40	3.0 × 10-1

^a Position on GenBank sequence NC_000016.4.

^b Calculated from a χ² test for the combined study and replicate samples.

^c Calculated as (ref_L /alt_L)/(ref_H /alt_H), where these are allele counts as in Table 4.

SNPs in bold are those with significant association with HDL cholesterol in both the study and replicate populations.

CETP, cholesteryl ester transfer protein dbSNP, single nucleotide polymorphism database; HDL, high-density lipoprotein.