Table 1.
Human PDI genes as listed in the Human Gene Nomenclature Committee (HGNC) database
| Gene name | Other aliases | Protein name | Chromosomal location | Amino acids |
|---|---|---|---|---|
|
AGR2 |
XAG-2, HAG-2, AG2, PDIA17 |
Anterior gradient protein 2 homolog |
7p21.3 |
175 |
|
AGR3 |
HAG3, hAG-3, BCMP11, PDIA18 |
Anterior gradient protein 3 homolog |
7p21.1 |
166 |
|
CASQ1 |
PDIB1 |
Calsequestrin-1 |
1q21 |
396 |
|
CASQ2 |
PDIB2 |
Calsequestrin-2 |
1p13.3-p11 |
399 |
|
DNAJC10 |
MTHr, ERdj5 |
DnaJ (Hsp40) homolog, subfamily C, member 10 |
2q32.1 |
793 |
|
ERP27 |
FLJ32115, ERp27, PDIA8 |
Endoplasmic reticulum resident protein 27 |
12p12.3 |
273 |
|
ERP29 |
ERp28, ERp31, ERp29, PDI-DB, PDIA9 |
Endoplasmic reticulum resident protein 29 |
12q24.13 |
261 |
|
ERP44 |
KIAA0573, PDIA10 |
Endoplasmic reticulum resident protein 44 |
9q22.33 |
406 |
|
P4HB |
DIA1, PROHB, DSI, GIT, PDI, PO4HB, P4Hb |
Protein disulfide-isomerase |
17q25 |
508 |
|
PDIA2 |
PDA2, PDIp |
Protein disulfide-isomerase A2 |
16p13.3 |
525 |
|
PDIA3 |
P58, ERp61, ERp57, ERp60, GRP57, PI-PLC, HsT17083 |
Protein disulfide-isomerase A3 |
15q15 |
505 |
|
PDIA4 |
ERP70, ERP72 |
Protein disulfide-isomerase A4 |
7q35 |
645 |
|
PDIA5 |
PDIR, FLJ30401 |
Protein disulfide-isomerase A5 |
3q21.1 |
519 |
|
PDIA6 |
P5, ERp5 |
Protein disulfide-isomerase A6 |
2p25.1 |
440 |
|
PDILT |
PDIA7, ERp65 |
Protein disulfide-isomerase-like protein of the testis |
16p12.3 |
584 |
|
TMX1 |
TMX, PDIA11 |
Thioredoxin-related transmembrane protein 1 |
14q22.1 |
280 |
|
TMX2 |
PDIA12 |
Thioredoxin-related transmembrane protein 2 |
11cen-q22.3 |
296 |
|
TMX3 |
FLJ20793, KIAA1830, PDIA13 |
Protein disulfide-isomerase TMX3 |
18q22 |
454 |
|
TMX4 |
DJ971N18.2, KIAA1162, PDIA14 |
Thioredoxin-related transmembrane protein 4 |
20p12 |
349 |
|
TXNDC5 |
MGC3178, FLJ21353, FLJ90810, EndoPDI, Hcc-2, ERp46, PDIA15 |
Thioredoxin domain-containing protein 5 |
6p24.3 |
432 |
| TXNDC12 | TLP19, ERP18, ERP19, hAG-1, AGR1, PDIA16 | Thioredoxin domain-containing protein 12 | 1p32.3 | 172 |
DNAJC10 has been included following identification of this gene in the PDI gene family. Synonyms of these genes have also been corrected.