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Paired genes exhibit a tighter transcriptional coordination during the budding yeast stress response. The average PCC was determined by bootstrapping random pairings of genes from the RRB and RP gene sets during a heat-shock (A and B), during the hyper-osmotic shock (C and D), and following treatment with menadione (E and F). The actual average PCC for the unpaired genes is indicated by *, for the paired but not adjacent genes by ·, and the adjacent paired genes by #.
