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. 2012 Nov 16;7(11):e49490. doi: 10.1371/journal.pone.0049490

Figure 1. smg-8 lacks the vulva phenotype associated with mutations in other NMD genes.

Figure 1

(A) Schematic representation of the tm2937 allele, which contains a 272 bp deletion and a 1 bp insertion. This deletion encompasses 22 bp upstream of the start site and the first two exons. Arrows indicate primers used for RT-qPCR (B) Vulval protrusion is one of the phenotypes of canonical smg genes. Left panel shows a wildtype vulva, middle panel shows a smg-8(tm2937) mutant and right panel shows a smg-1(r861) mutant. smg-8 mutants are similar to wild-type and not to smg-1. Arrowheads denote the vulva.