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. 2012 Nov 16;7(11):e49548. doi: 10.1371/journal.pone.0049548

Table 1. Defining the sixteen latent classes and calculating their sero-prevalence rates.

Class No. Latent class definition Seroprevalence
Median (95% CI)* Mean
Class 1 Mtb**+, All antibodies+ 15.9 (9.8, 24.0) 16.2
Class 2 Mtb+, ESAT6+, CFP10+, PE-PGRS11+ 1.3 (0.1, 4.3) 1.5
Class 3 Mtb+, ESAT6+, CFP10+, PE-PGRS17+ 0.4 (0.0, 2.1) 0.6
Class 4 Mtb+, ESAT6+, PE-PGRS11+, PE-PGRS17+ 0.8 (0.0, 4.4) 1.2
Class 5 Mtb+, CFP10+, PE-PGRS11+, PE-PGRS17+ 3.1 (0.2, 10.3) 3.7
Class 6 Mtb+, ESAT6+, CFP10+ 0.8 (0.0, 3.2) 1.0
Class 7 Mtb+, ESAT6+, PE-PGRS11+ 0.6 (0.0, 3.2) 0.9
Class 8 Mtb+, ESAT6+, PE-PGRS17+ 0.5 (0.0, 2.3) 0.7
Class 9 Mtb+, CFP10+, PE-PGRS11+ 0.5 (0.0, 2.6) 0.7
Class 10 Mtb+, CFP10+, PE-PGRS17+ 0.4 (0.0, 2.3) 0.6
Class 11 Mtb+, PE-PGRS11+, PE-PGRS17+ 11.9 (4.2, 18.5) 11.7
Class 12 Mtb+, ESAT6+ 0.7 (0.0, 3.5) 1.0
Class 13 Mtb+, CFP10+ 0.5 (0.0, 2.6) 0.7
Class 14 Mtb+, PE-PGRS11+ 0.7 (0.0, 3.1) 0.9
Class 15 Mtb+, PE-PGRS17+ 4.8 (0.2, 11.8) 5.1
Class 16 Mtb-, All antibodies- 53.6 (44.6, 62.8) 53.6

Latent class definition and the seroprevalence rate for each class thus defined in the LCA model for studying TB in Asian elephants in southern India. The latent classes are different combinations of the latent variables (i.e. true presence of the antibodies) which are present if M. tuberculosis infection is present. *Median estimate is at the 50% quantile while the 2.5% and 97.5% quantiles define a 95% credible interval (CI). **M. tuberculosis infection.