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. 2012 Nov 16;7(11):e49548. doi: 10.1371/journal.pone.0049548

Table 2. Sensitivity (DSe) and specificity (DSp) of the five serological tests used in the study.

Test w.r.t.** DSe DSp
Median (95% CI)* Median (95% CI)*
RT At least 1 antibody 48.6 (37.2, 61.0) 99.3 (96.7, 99.9)
ESAT6 44.6 (33.9, 56.4) 95.2 (90.4, 98.2)
CFP10 46.5 (36.0, 58.1) 93.0 (87.8, 96.6)
PE_PGRS11 79.8 (66.7, 90.8) 98.5 (93.6, 99.9)
PE_PGRS17 84.5 (75.2, 91.3) 89.6 (79.4, 98.4)
ESAT6 At least 1 antibody 88.8 (73.5, 97.5) 95.1 (90.5, 98.2)
ESAT6 91.3 (74.8, 99.5) 95.2 (90.4, 98.2)
CFP10 77.0 (61.9, 88.5) 88.9 (83.2, 93.6)
PE_PGRS11 85.0 (71.7, 94.0) 75.9 (68.2, 82.3)
PE_PGRS17 80.3 (66.7, 90.2) 65.7 (57.8, 73.1)
CFP10 At least 1 antibody 88.8 (73.5, 97.5) 95.3 (90.8, 98.2)
ESAT6 75.2 (60.0, 87.1) 91.2 (85.7, 95.2)
CFP10 92.3 (76.9, 99.5) 93.0 (87.8, 96.6)
PE_PGRS11 85.2 (71.5, 94.0) 76.0 (68.5, 82.6)
PE_PGRS17 81.5 (67.9, 91.4) 66.2 (58.3, 73.5)
PE_PGRS11 At least 1 antibody 50.1 (38.2, 62.1) 93.9 (88.8, 97.2)
ESAT6 47.1 (35.8, 58.7) 91.5 (85.9, 95.4)
CFP10 49.1 (38.0, 60.2) 89.4 (83.5, 93.7)
PE_PGRS11 97.6 (88.6, 99.8) 98.5 (93.6, 99.9)
PE_PGRS17 87.1 (77.6, 93.6) 81.4 (73.4, 88.1)
PE_PGRS17 At least 1 antibody 44.4 (32.5, 57.6) 91.6 (85.5, 96.0)
ESAT6 42.2 (30.9, 54.8) 89.6 (83.0, 94.1)
CFP10 44.8 (33.6, 57.1) 87.8 (81.5, 92.7)
PE_PGRS11 82.7 (68.2, 94.3) 91.9 (85.3, 96.5)
PE_PGRS17 97.2 (88.5, 99.9) 89.6 (79.4, 98.7)

The LCA model was used to calculate the DSe and DSp of each test w.r.t. the antibody it is designed to detect as also presence of at least one antibody. *The Median estimate refers to the 50% quantile while the 2.5% and 97.5% quantiles define a 95% credible interval (CI). ** With respect to.