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. 2012 Nov 16;7(11):e50372. doi: 10.1371/journal.pone.0050372

Table 1. Summary of counts, fetus-time at risk, and rates per 10,000 for variables stratified on spontaneous abortion (SAB) vs. other pregnancy outcomes for the Danish National Birth Cohort (1996–2002).

Not SAB SAB
N Fetus-days* N Fetus-days* Rate of SAB/10,000 fetus-days
Letigen use
None 92,930 6,547,875 4,408 108,617 6.6
Pre-conception only 219 17,680 13 274 7.2
Both pre-conception and early pregnancy 270 21,311 17 346 7.8
Early pregnancy only 37 2,725 5 71 17.9
Missing timing 4 327 0 0
Gestational age at entry (completed weeks)
5–8 29,102 2,766,449 2,878 76,695 10.1
9–12 40,260 2,886,894 1,435 30,006 4.9
13–16 18,680 839,147 118 2,465 1.4
17–20 5,418 97,428 12 142 1.2
Maternal age (years)
15–19 987 64,538 40 1,120 6.1
20–24 11,399 818,878 464 11,806 5.6
25–29 38,814 2,797,147 1,609 40,299 5.7
30–34 31,581 2,183,600 1,506 37,775 6.8
35–39 9,756 666,161 683 15,781 10.0
40–46 923 59,594 141 2,527 22.7
Gravidity
No prior pregnancy 30,573 2,215,384 966 25,344 4.3
≥1 prior pregnancy 57,061 3,988,842 2,171 55,864 5.4
Missing 5,826 385,692 1,306 28,100
Planned pregnancy
Planned 66,705 4,785,563 2,440 63,180 5.0
Partially planned 11,080 765,877 371 9,349 4.8
Not planned 9,859 654,187 328 8,757 4.9
Missing 5,816 384,291 1,304 28,022
Infertility treatment
Yes 5,700 386,549 167 4,581 4.3
No 81,923 5,817,343 2,972 76,705 5.0
Missing 5,837 386,026 1,304 28,022
Prepregnancy body mass index
Underweight (<18.5) 3,870 272,001 163 4,507 5.9
Normal (18.5–24.9) 58,493 4,138,880 2,076 52,949 5.0
Overweight (25.0–29.9) 16,707 1,182,334 613 15,805 5.1
Obese (> = 30.0) 7,160 510,755 255 7,114 4.9
Missing 7,230 485,948 1,336 28,933
Exercise (hours/week)
None 55,769 3,920,465 1,589 43,290 4.0
>0 to <2 17,494 1,241,710 626 16,024 5.0
> = 2 to <4 9,599 697,141 543 13,291 7.6
> = 4 to <7 3,504 254,635 256 5,895 9.8
> = 7 1,271 91,193 124 2,774 13.2
Missing 5,823 384,774 1,305 28,034
Smoked during pregnancy (cigarette equivalents/day § )
None 67,521 4,781,746 2,342 60,576 4.8
>0 to 10 14,741 1,046,138 569 14,975 5.4
>10 5,373 376,952 224 5,656 5.9
Missing 5,825 385,082 1,308 28,101
Alcohol during pregnancy (drinks/week)
No drinks 48,727 3,507,924 1,560 41,792 4.4
>0 to <4 37,112 2,578,283 1,427 36,548 5.5
> = 4 1,823 120,506 152 2,946 12.3
Missing 5,798 383,205 1,304 28,022
Coffee (cups/day)
None 48,693 3,507,238 1,477 40,674 4.2
>0 to <4 27,519 1,922,961 1,016 25,636 5.2
4 to <8 8,493 575,907 440 10,171 7.5
> = 8 2,932 198,957 203 4,734 10.0
Missing 5,823 384,855 1,307 28,093
Tea (cups/day)
None 32,583 2,311,375 1,200 31,184 5.1
>0 to <4 39,427 2,793,264 1,334 34,381 4.7
4 to <8 11,928 842,605 428 11,156 5.0
> = 8 3,699 257,799 176 4,534 6.7
Missing 5,823 384,875 1,305 28,053
Cola (liters/week)
None 29,967 2,125,366 1,136 30,021 5.3
>0 to <1 42,896 3,026,527 1,310 33,935 4.3
> = 1 14,758 1,051,921 689 17,210 6.4
Missing 5,839 386,104 1,308 28,142
*

Observed fetus days at risk (i.e. time from entry to outcome, censoring, or end of risk period).

Pre-conception includes the 4 weeks prior to last menstrual period through gestational age 2 completed weeks, early pregnancy includes gestational age 3–13 completed weeks, missing time includes Letigen use during an undefined time.

§

1 cigarette = 1 cigarette equivalent, 1 cherrot = 2 cigarettes equivalents, 1 cigar = 2 cigarette equivalents, 1 pipe = 1.5 cigarette equivalents.