. Author manuscript; available in PMC: 2013 Nov 16.

Published in final edited form as: ACS Chem Biol. 2012 Aug 21;7(11):1830–1839. doi: 10.1021/cb3003013

Table 3.

Paroxetine enhances βAR-mediated cardiomyocyte contractility

	Control	Paroxetine	P-value
Baseline before isoproterenol
Max. contraction amplitude (% cell length)	4.6 ± 0.4	4.5 ± 0.4	0.988
Max. shortening velocity (μm s⁻¹)	−0.81 ± 0.07	−0.77 ± 0.09	0.725
Max. relengthening velocity (μm s⁻¹)	0.60 ±0.07	0.58 ± 0.08	0.834
Half-time of relaxation (ms)	54.1 ± 3.1	65.9 ± 7.3	0.143
After isoproterenol
Max. contraction amplitude (% cell length)	12.3 ± 0.7	15.8 ± 1.3	0.0191
% increase in contraction amplitude	180.9 ± 13.8	260.2 ± 19.0	0.0018

Values represent the mean ± SEM for n=18 cardiomyocytes.