Table 1.
Mammary carcinoma multiplicity phenotypes (mean mammary carcinomas per rat ± SD) by genotype for WF.COP Chr 2 congenic lines used to map Mcs1b to 1.8 Mb
WF.COP Chr2 region | Line | COP/COP (COP/WF) | n | WF/WF | n | P value* |
---|---|---|---|---|---|---|
D2Uwm17/g2UL2-30 | T† | 3.5±2.2 | 21 | 8.3±3.3 | 19 | 0.0010 |
D2Uwm17/D2Ulb4 | F3 | 9.6±4.1 | 32 | 8.8±3.5 | 32 | 0.8433 |
D2Mgh2/g2UL1-5 | N3 | 3.4±2.0 | 25 | 7.8±3.1 | 25 | 0.0001 |
N3 | (5.5±3.6) | 15 | 0.0413 | |||
D2Ulb4/ENSRNOSNP2740854 | W2 | 6.0±1.8 | 18 | 5.9±3.2 | 9 | 0.8498 |
D2Rat116/ENSRNOSNP2740854 | U2 | 5.7±3.9 | 6 | 6.3±3.3 | 12 | 0.8866 |
g2UL2-27/D2Rat201 | I4 | 9.3±3.0 | 19 | 7.9±3.7 | 13 | 0.2470 |
Abbreviations: WF, Wistar Furth; COP, Copenhagen; Chr, chromosome
P values from Mann Whitney tests
Line T phenotype published previously by Haag et al. Cancer Research, 63:5808–5812, 2003