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. Author manuscript; available in PMC: 2013 Nov 15.
Published in final edited form as: Cancer Res. 2012 Aug 31;72(22):5833–5842. doi: 10.1158/0008-5472.CAN-12-1229

Figure 1. RGS4 is downregulated in BECs during KSHV infection.

Figure 1

Primary human dermal BECs were infected with KSHV for two days and the expression of LANA (A) and RGS4 (B) was determined by qRT-PCR. Results are shown as average relative expression ± standard deviation. ***, p < 0. 001. (C) Western blot analyses showing downregulation of RGS4 protein in KSHV-infected BECs. (D) Immunofluorescent staining against RGS4 in BECs that were infected with GFP-labeled KSHV revealed that RGS4 was downregulated in only GFP-positive, KSHV-infected BECs (arrowhead), but not in uninfected neighboring cells (arrow). All experiments were repeated three times and comparable outcome was obtained.