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. Author manuscript; available in PMC: 2013 Nov 15.
Published in final edited form as: Clin Cancer Res. 2012 Aug 29;18(22):6110–6121. doi: 10.1158/1078-0432.CCR-12-2130

Figure 1. The upregulation of IDO in glioma is associated with a decreased overall lifespan in patients.

Figure 1

Data was isolated from the Repository of Molecular Brain Neoplasia Data (REMBRANDT) and represents the analysis of 343 different glioma patients. (A) The Kaplan-Meier survival curve for IDO1 was plotted for upregulated (triangle), intermediate (square) and downregulated (circle) expression over time. (B) Upregulated, (C) intermediate and (D) downregulated IDO expression in glioma was correlated to the percentage of grade II (Astro II), grade III (Astro III) or glioblastoma multiforme [(GBM) grade IV astrocytoma]. *p < 0.05; **p < 0.005