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Lysis followed the rule of missing-self recognition. (A) CD107a degranulation was measured on KIR2DL1, KIR2DL2/3, and KIR3DL3 subsets of NK cells co-cultured with MLL-rearranged leukemia cells pre-coated with 1000 ng/mL lintuzumab or (B) 10 ng/mL XmAb5574 with or without 10 µg/mL panMHCI antibody. The data are mean ± S.E.M. of four independent experiments. *p<0.05 **p<0.01 ***p<0.001.
