Table A1.

Safe Prescribing Features for Oral Chemotherapies

Features
General
Drug name, dose form (ie, pill strength), no. to be taken at one time (eg, two tablets per dose)
Route
Frequency
No. dispensed
No. of refills
Sig (ie, free text)
Special instructions (eg, take with food)
Explicit dose calculations and cycle notation
Dosing rule (fixed dose, weight based, body surface area based)
Dose calculation along with height and weight (if appropriate)
Cycle number
Diagnosis and goal of therapy
Diagnosis
Goal of therapy (curative/adjuvant v palliative/metastatic)
Research protocol number (if appropriate)
Additional patient instructions, including safe handling and irregular dosing patterns
Decision support and safety features
Drug allergy checks
Drug interaction checks
Dose-limit warnings (daily, weekly, cumulative)
Geriatric and renal dose warnings
Second physician double check