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. 2012 Dec;343(3):568–577. doi: 10.1124/jpet.112.198747

Fig. 8.

Fig. 8.

Histamine H3 and H4 receptor activation inhibits Ca2+-dependent NE exocytosis from cardiac sympathetic nerves via inhibition of PKG and consequent reduction of PKG-dependent PDE3 inhibition. NP, natriuretic peptides; pGC, particulate guanylyl cyclase; cGMP, cyclic GMP; [Ca2+]i, intracellular calcium.