Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
LC-MS/MS spectrum of the GSHEE adduct formed by human liver microsomes. Human liver microsomes were incubated with tamoxifen and GSHEE in the presence or absence of NADPH. The incubation conditions and the analysis are as described under Materials and Methods. A, the extracted ion chromatogram for the OHtam quinone methide-GSHEE adduct eluting at 16.6 min. B, the MS/MS spectrum of the peak eluting at 16.6 min with m/z 719. C, the MS2 of the m/z 719 ion.
