Fig. 4.

The analgesic activity of compound C in formalin test. Vehicle and different doses of the compound C were administered 30 min prior to subplantar injection of formalin and the time spent for licking was measured during a 0-5 min (acute phase) and 20-30 min (chronic phase) period starting after formalin injection. Morphine (10 mg/kg, i.p.) was used as reference drug. Data are mean ± SEM of 6 animals in each group. * P <0.05; ** P < 0.01; *** P < 0.001 significantly different from control group (ANOVA with Scheffe post hoc test).