. Author manuscript; available in PMC: 2012 Nov 18.

Published in final edited form as: Free Radic Res. 2010 Oct 13;45(2):188–200. doi: 10.3109/10715762.2010.522575

Table III.

Levels of MnTnHex-2-PyP⁵⁺ in mouse tumour and muscle expressed in µM in tissue determined by LC/ESI-MS/MS method. Tumours and muscle tissues were collected in a 4T1 mouse breast tumour study. Tumours were grown in Balb/c mice (n = 15). Mice were injected twice daily with MnP and ascorbate for 2 weeks from the moment the tumour size reached ~100–200 mm³, until its volume increased ~5-fold.

PyP⁵⁺	MnTnHex-2-PyP⁵⁺/ µM in tissue (mean)	SD	Range
Tumor (MnP)	1.65	1.29	0.735 – 5.89
Muscle (MnP)	0.31	0.07	0.166 – 0.417
Tumour (MnP + asc)	2.20	0.84	1.01 – 3.81
Muscle (MnP + asc)	0.48	0.16	0.231 – 0.849