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. Author manuscript; available in PMC: 2012 Nov 18.
Published in final edited form as: Free Radic Res. 2010 Oct 13;45(2):188–200. doi: 10.3109/10715762.2010.522575

Table III.

Levels of MnTnHex-2-PyP5+ in mouse tumour and muscle expressed in µM in tissue determined by LC/ESI-MS/MS method. Tumours and muscle tissues were collected in a 4T1 mouse breast tumour study. Tumours were grown in Balb/c mice (n = 15). Mice were injected twice daily with MnP and ascorbate for 2 weeks from the moment the tumour size reached ~100–200 mm3, until its volume increased ~5-fold.

PyP5+ MnTnHex-2-PyP5+/
µM in tissue (mean)
SD Range
Tumor (MnP) 1.65 1.29 0.735 – 5.89
Muscle (MnP) 0.31 0.07 0.166 – 0.417
Tumour (MnP + asc) 2.20 0.84 1.01 – 3.81
Muscle (MnP + asc) 0.48 0.16 0.231 – 0.849