Table 3.
Cross-Sectional Area Changes in the Trained Arm in Response to RT by LEPR 668 A>G Genotype
| Phenotype | AA N=62 | GG/GA N=166 |
|---|---|---|
| Baseline whole arm cross sectional area (cm2) | 6178.06 ± 90.6 | 6252.55±56.39 |
| Post RT whole arm cross sectional area (cm2) | 6744.40±97.0 | 6996.97±60.91 |
| Absolute change (cm2) | 566.33±55.1* | 744.42±34.25 |
| Relative change (%) | 9.9±0.96* | 12.2±0.59 |
| Baseline whole muscle cross sectional area (cm2) | 5308.85±168.68 | 5413.44±104.88 |
| Post RT whole muscle cross sectional area (cm2) | 5869.33±175.58 | 6138.85±109.17 |
| Absolute change (cm2) | 560.48±51.2* | 725.39±31.84 |
| Relative change (%) | 12.17±1.05 | 14.17±0.65 |
| Baseline subcutaneous fat cross sectional area (cm2) | 2262.04±82.39 | 2291.36±51.23 |
| Post RT subcutaneous fat cross sectional area (cm2) | 2211.36±87.42 | 2380.40±54.36 |
| Absolute change(cm2) | −50.68±37.61* | 89.03±23.39 |
| Relative change (%) | −1.95±1.86* | 4.82±1.16 |
Values are means ±SE. Covariates included BMI and age with LEPR genotype set as the fixed factor. LEPR, Leptin Receptor; A, LEPR A668 allele; G, LEPR G668 allele
*
P < 0.05, AA vs GG/GA