Table 4.
Volume Changes in Trained Arm in Response to Resistance Training by LEPR 668 A>G Genotype
| Phenotype | AA N=62 | GG/GA N=122 |
|---|---|---|
| Baseline whole arm volume (mm3) | 578037.66±8449.74 | 583481.81±5254.01 |
| Post RT whole arm volume (mm3) | 630588.66±8917.96 | 651499.52±5545.24 |
| Absolute change (mm3) | 52551.01±5070.75* | 68017.71±3153.02 |
| Relative Change (%) | 9.78±0.95* | 12.02±0.59 |
| Baseline whole muscle volume (mm3) | 494808.01±15341.97 | 504493.84±9557.60 |
| Post RT whole muscle volume (mm3) | 547205.86±15866.25 | 571038.04±9884.22 |
| Absolute change (mm3) | 52321.87±5125.05* | 67687.05±3186.78 |
| Relative Change (%) | 12.09±1.05 | 13.94±0.65 |
| Baseline subcutaneous fat volume (mm3) | 211364.22±7549.02 | 211894.23±4702.82 |
| Post RT subcutaneous fat volume (mm3) | 206319.65±7937.28 | 219719.84±4944.70 |
| Absolute change (mm3) | −5224.73±5923.98* | 10599.89±3683.57 |
| Relative Change (%) | −2.05±1.8* | 4.61±1.1 |
Values are means ±SE. Covariates included BMI and age with LEPR genotype set as the fixed factor. LEPR, Leptin Receptor; A, LEPR A668 allele; G, LEPR G668 allele
*
P < 0.05, AA vs GG/GA