Table 1.

List of some relevant secretomics studies and outcomes.

Study (year)	Field of study	Outcome	Ref.
An et al. (2010)	Biomedical science	Defined the role of a serine protease in age-related macular degeneration	[1]
Formolo et al. (2011)	Cancer	Defined potential proteins involved in brain tumor invasion	[2]
Korpal et al. (2011)	Cancer	Defined a novel mechanism of breast cancer metastasis	[3]
Wu et al. (2010)	Cancer	Defined a useful set of potential biomarkers for cancer in general and for specific cancers	[5]
Bobadilla Fazzini et al. (2011)	Metal extraction	Defined novel proteins to improve bioleaching and metal extraction	[8]
Bernay et al. (2009)	Brain	Discovered new bioactive neuropeptides	[11]
Jami et al. (2010)	Biotechnology	Improvement of penicillin production	[18]
Herpoel-Gimbert et al. (2008)	Biotechnology	Characterization of Trichoderma-secreted cellulases for the biofuel industry	[21]
Maxwell et al. (2008)	Cancer	Defined role of intracellular secreted proteins in tumor progression	[26]
Pant et al. (2012)	Biomedical science	Comprehensive review of the role of exosomes in health and disease	[29]
Gronborg et al. (2006)	Cancer	Defined potential pancreatic cancer biomarkers	[36]
Roelofsen et al. (2009)	Technique	Developed novel method to study tissue explant secretomes	[60]
Takeda et al. (2011)	Technique	Developed novel technique to study in vivo secretome in the brain	[70]
Lum et al. (2011)	Bioinformatics	Developed a comprehensive knowledge database for the fungal secretome	[72]