Figure 2.
Characterization of Df-TRC105-800CW and the tumor model. A. Flow cytometry analysis of TRC105 and Df-TRC105-800CW in HUVECs (CD105-positive) and MCF-7 human breast cancer cells (CD105-negative) at different concentrations. Data from various control experiments are also shown. B. Serial bioluminescence images of tumor-bearing mice after intravenous injection of fLuc-4T1 cells. C. Total photon flux of the bioluminescence signal from the lung (n = 8).