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. Author manuscript; available in PMC: 2014 Jan 19.
Published in final edited form as: Mol Pharm. 2012 Jul 19;9(8):2339–2349. doi: 10.1021/mp300277f

Figure 2.

Figure 2

Characterization of Df-TRC105-800CW and the tumor model. A. Flow cytometry analysis of TRC105 and Df-TRC105-800CW in HUVECs (CD105-positive) and MCF-7 human breast cancer cells (CD105-negative) at different concentrations. Data from various control experiments are also shown. B. Serial bioluminescence images of tumor-bearing mice after intravenous injection of fLuc-4T1 cells. C. Total photon flux of the bioluminescence signal from the lung (n = 8).