Table 1.
Estimated radiation absorbed doses to an adult female after intravenous injection of 89Zr-Df-TRC105-800CW (n = 4).
| Target Organ | Total (mSv/MBq) |
SD (mSv/MBq) |
Total (rem/mCi) |
SD (rem/mCi) |
|---|---|---|---|---|
| Adrenals | 9.53E−02 | 7.17E−03 | 3.52E−01 | 2.67E−02 |
| Brain | 2.08E−03 | 2.45E−04 | 7.68E−03 | 9.13E−04 |
| Breasts | 5.97E−02 | 5.48E−03 | 2.21E−01 | 2.05E−02 |
| Gallbladder Wall | 1.26E−01 | 1.09E−02 | 4.65E−01 | 4.11E−02 |
| LLI Wall | 8.10E−03 | 8.79E−04 | 3.00E−02 | 3.25E−03 |
| Small Intestine | 2.34E−02 | 1.83E−03 | 8.67E−02 | 6.85E−03 |
| Stomach Wall | 5.59E−02 | 4.46E−03 | 2.07E−01 | 1.66E−02 |
| ULI Wall | 3.28E−02 | 2.64E−03 | 1.21E−01 | 1.00E−02 |
| Heart Wall | 8.34E−01 | 8.78E−02 | 3.09E+00 | 3.26E−01 |
| Kidneys | 5.24E−02 | 4.12E−03 | 1.94E−01 | 1.52E−02 |
| Liver | 4.40E−01 | 4.21E−02 | 1.63E+00 | 1.54E−01 |
| Lungs | 1.07E−01 | 9.31E−03 | 3.97E−01 | 3.43E−02 |
| Muscle | 3.12E−02 | 2.94E−03 | 1.15E−01 | 1.09E−02 |
| Ovaries | 1.18E−02 | 1.11E−03 | 4.36E−02 | 4.07E−03 |
| Pancreas | 9.18E−02 | 6.92E−03 | 3.40E−01 | 2.57E−02 |
| Red Marrow | 3.07E−02 | 2.55E−03 | 1.14E−01 | 9.75E−03 |
| Osteogenic Cells | 2.46E−02 | 2.10E−03 | 9.10E−02 | 7.80E−03 |
| Skin | 1.56E−02 | 1.31E−03 | 5.76E−02 | 4.88E−03 |
| Spleen | 3.48E−02 | 2.94E−03 | 1.29E−01 | 1.08E−02 |
| Thymus | 1.35E−01 | 1.37E−02 | 4.98E−01 | 5.19E−02 |
| Thyroid | 1.50E−02 | 1.70E−03 | 5.53E−02 | 6.32E−03 |
| Bladder Wall | 7.57E−03 | 8.46E−04 | 2.80E−02 | 3.13E−03 |
| Uterus | 1.23E−02 | 1.12E−03 | 4.56E−02 | 4.13E−03 |
| Total body | 4.24E−02 | 3.30E−03 | 1.57E−01 | 1.23E−02 |