Table 1.
Clinical characteristics of the patients
| Patient 1 | Patient 2 | Patient 3 | |
|---|---|---|---|
| Ages (yr) |
26 |
63 |
42 |
| Gender (M/F) |
M |
F |
M |
| Cough duration (month) |
42 |
24 |
25 |
| Heartburn |
Yes |
Yes |
No |
| Regurgitation |
Yes |
Yes |
Yes |
| Cough symptom score | |||
| Daytime |
3 |
4 |
3 |
| Nighttime |
1 |
2 |
2 |
| Cough threshold to capsaicin | |||
| C2(μmol/L) |
0.49 |
0.49 |
1.95 |
| C5(μmol/L) |
31.2 |
1.95 |
7.8 |
| FEV1 (%predicted) |
99.1 |
101.8 |
86.1 |
| FVC (%predicted) |
96.9 |
104.0 |
96.1 |
| FEV1/FVC (%) |
89.5 |
83.8 |
75.0 |
| PD20FEV1(μmol) | >7.8 | >7.8 | >7.8 |
FEV1: forced expiratory volume in one second; FVC: forced vital capacity; PD20FEV1: the cumulative provocative dose of histamine causing a 20% fall in FEV1.