Table 1.
Descriptive demographics and basic measures for diagnostic groups and iPIB-PET classification
| Diagnosis | iPIB-PET status | Sample size | Age (SD) in years | Gender (f/m) | MMSE (SD) | ApoE genotype (ϵ4−/ϵ4+) | Education (SD) in years | CSF Aβ1–42, pg/ml | CSF total tau, pg/ml | CSF p-tau, pg/ml |
| HC | iPIB-PET(−) | 73 | 75.6 (5.4) | 38/35 | 29.0 (1.1) | 69/4** | 15.5 (SD = 2.8) | 244.7 (27.6)** | 62.0 (23.0)* | 20.5 (8.0)* |
| iPIB-PET(+) | 51 | 76.4 (5.1) | 21/30 | 29.2 (1.1) | 27/24 | 16.0 (3.0) | 152.0 (27.6) | 79.5 (37.6) | 31.0 (19.1) | |
| MCI | iPIB-PET(−) | 63 | 74.8 (8.2) | 15/48 | 27.3 (1.7) | 25/11** | 15.7 (3.0) | 244.1 (26.9)** | 62.6 (23)** | 20.0 (7.6)** |
| iPIB-PET(+) | 166 | 74.4 (7.4) | 63/103 | 26.8 (1.8) | 55/111 | 15.9 (2.9) | 136.4 (26.0) | 116.5 (62.8) | 40.5 (17.5) | |
| AD | All subjects pooled | 112 | 74.9 (8.1) | 47/65 | 23.6 (1.9) | 36/76 | 15.1 | 142.5 (39.6) | 121.5 (57.5) | 102.4 (19.8) |
Note: f, female, m, male; **P ≤ 0.001 and *P ≤0.01 for comparison with iPIB-PET(+) within diagnostic group.