Table 3.
Rate of FDG-PET change: results of the mixed-effect analysis for the comparison between iPIB-PET(+) and iPIB-PET(−) in MCI and HC
| ROI | Diagnosis | iPIB-PET group | % Annual change in iPIB-PET score per year | Δ In % Annual change between iPIB-PET(−) versus iPIB-PET(+) in iPIB-PET score per year | B (SE) of Δ in annual volume change between iPIB-PET(−) versus iPIB-PET(+) in iPIB-PET score per year |
| Inferior/middle temporal gyrus | HC | PIB(−) | 0.2 | −0.1 | Greater than −0.01 (0.02) |
| PIB(+) | 0.1 | ||||
| MCI | PIB(−) | −0.8 | −2.3 | −0.03 (0.02) | |
| PIB(+) | −2.1 | ||||
| Angular gyrus | HC | PIB(−) | −1.0 | 0.1 | 0.02 (0.03) |
| PIB(+) | 0.0 | ||||
| MCI | PIB(−) | −1.1 | −1.1 | −0.02 (0.02) | |
| PIB(+) | −2.1 | ||||
| Posterior cingulum | HC | PIB(−) | −0.5 | 0.3 | <0.01 (0.01) |
| PIB(+) | −0.2 | ||||
| MCI | PIB(−) | −0.8 | −1.5 | −0.02 (0.01) | |
| PIB(+) | −2.3 | ||||
| Frontal orbital | HC | PIB(−) | −0.6 | 0.6 | 0.01 (0.01) |
| PIB(+) | 0.0 | ||||
| MCI | PIB(−) | −1.3 | −0.4 | Greater than −0.01 (0.01) | |
| PIB(+) | −1.7 |