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Identification of a mutation in the gene for the conserved kinase SRPK. (A) Generation of female germline clones to screen for karyosome mutants. (B) Deficiency mapping of the female sterile mutation in 2R-129-09. The deleted genomic regions of deficiencies are indicated by the absence of lines and parentheses. The transgene (CH322-130M04) rescued the mutation. (C) A nonsense srpk mutation was indentifed in 2R-129-09 (the position marked by the red cross in B).
