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. 2012 Oct 1;125(19):4457–4462. doi: 10.1242/jcs.107979

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© 2012. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial Share Alike License (http://creativecommons.org/licenses/by-nc-sa/3.0), which permits unrestricted non-commercial use, distribution and reproduction in any medium provided that the original work is properly cited and all further distributions of the work or adaptation are subject to the same Creative Commons License terms.

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Fig. 3. — Spindle microtubule assembly is severely compromised in the srpk mutant. (A) Metaphase I spindles in mature oocytes. (i) Robust bipolar spindles; (ii) no or short microtubules; (iii) one or a few microtubule bundles; and (iv) other abnormal spindles, including multipolar spindles and/or spindles with loose and/or weak microtubules. (B) Spindle morphology in wild-type and srpk oocytes. (C) Total spindle microtubule intensity (means±s.e.m.) in mature oocytes from wild-type and srpk mutant flies. (D) FISH using the pericentromeric dodeca satellite on chromosome 3 as a probe. Arrowheads indicate the positions of the centromere 3. The inserts show FISH signals alone in a higher magnification. (E) Frequency of mono-oriented homologous centromeres. Scale bars: 10 µm.