FIGURE 2.

Using gene expression data to delineate subnetworks within larger protein–protein interaction networks determined by the yeast two hybrid method. Left panel: part of the vesicle trafficking PPI interactome, with nodes colored according to average expression level of the corresponding genes in seedling tissue (root and shoot) treated with 10 μM ABA (Goda et al., 2008). Right panel: the same network colored according to the average expression level of the same genes in purified mesophyll and guard cells treated with 100 μM ABA for 4 h (Yang et al., 2008). The genes for different proteins exhibit stronger expression levels in these distinct tissues, highlighting potential protein–protein interaction subnetworks in these different kinds of tissues. Gray nodes denote that no expression information is available.