TABLE 1.

List of the down-regulated or up-regulated genes, involved in thrombosis, in the PAK1 knock-out MEFs compared to its wild-type controls

Refseq	Gene symbol	Fold change	Regulation	Gene description
NM_009378	Thbd	7.86	Down	Thrombomodulin
NM_011058 NM_001083316	Pdgfra	5.04	Down	Platelet-derived growth factor receptor, α-polypeptide
NM_009255	Serpine2	3.27	Down	Serine (or cysteine) peptidase inhibitor, clade E, member 2
NM_010171	F3	2.53	Down	Coagulation factor III
NM_008610	Mmp2	2.51	Down	Matrix metallopeptidase 2
NM_031168	Il6	2.42	Down	Interleukin 6
NM_009506	Vegfc	2.37	Down	Vascular endothelial growth factor C
NM_001110504 NM_007600	Capn1	4.88	Up	Calpain 1
NM_011576	Tfpi	3.46	Up	Tissue factor pathway inhibitor
NM_011198	Ptgs2	3.26	Up	Prostaglandin-endoperoxide synthase 2
NM_010217	Ctgf	2.70	Up	Connective tissue growth factor
NM_008873	Plau	2.25	Up	Plasminogen activator, urokinase
NM_009931	Col4a1	2.08	Up	Collagen, type IV, α1
NM_019521	Gas6	2.02	Up	Growth arrest specific 6
NM_011057	Pdgfb	2.01	Up	Platelet-derived growth factor, B polypeptide
NM_008969	Ptgs1	2.01	Up	Prostaglandin-endoperoxide synthase 1