TABLE 1.
Summary table of genes involved in hf development, up-regulated, and down-regulated with fold change in each data set
NA, not applicable.
| Cyp26b1−/− |
En1Cre;Cyp26b1f/− |
|||
|---|---|---|---|---|
| E16.5 RNA-Seq | E18.5 microarray | E18.5 RNA-Seq dermis | E18.5 RNA-Seq epidermis | |
| Crabp1 | Up-regulated 2.1 | Up-regulated 2.7 | NA | NA |
| Crabp2 | Up-regulated 2.7 | Up-regulated 13.1 | Up-regulated 12.4 | NA |
| CTNNA2 | NA | NA | Up-regulated 61.9 | NA |
| Ctnnb1 | NA | NA | Up-regulated 2533.8 | NA |
| Ctnnd1 | Up-regulated 2.3 | NA | NA | NA |
| Ctnnd2 | Up-regulated 2.1 | Down-regulated − 2.7 | Up-regulated 64.9 | NA |
| Dkk1 | NA | NA | NA | NA |
| Dkk4 | Up-regulated 2.9 | Up-regulated 2.1 | NA | NA |
| Dkkl1 | NA | Up-regulated 5.4 | NA | NA |
| Dlx3 | NA | NA | Down-regulated − 6.2 | NA |
| Eda | NA | NA | NA | NA |
| Egfr | Up-regulated 2.5 | NA | NA | NA |
| FoxE1 | NA | NA | Down-regulated − 30.1 | NA |
| FoxN1 | NA | NA | Down-regulated − 8.3 | NA |
| Gata3 | NA | NA | Down-regulated − 5.0 | NA |
| Igf-1 | Up-regulated 2.3 | NA | NA | NA |
| Igfbp5 | NA | NA | NA | NA |
| Lef1 | NA | NA | NA | NA |
| Lhx2 | Down-regulated − 2.2 | Down-regulated − 4.1 | NA | Down-regulated − 7.9 |
| Lymphotoxin B | NA | NA | NA | NA |
| Runx1 | NA | NA | NA | Down-regulated − 7.1 |
| Runx3 | NA | NA | NA | NA |
| Sostdc1 | NA | NA | NA | NA |
| Sox2 | NA | NA | NA | NA |
| Sox18 | NA | Down-regulated − 2.0 | NA | Down-regulated − 6.9 |
| Sox21 | NA | Down-regulated − 3.7 | Down-regulated − 9.7 | Down-regulated − 6.8 |
| Stra6 | Up-regulated 72.3 | Up-regulated 7.7 | NA | NA |
| Wnt4 | NA | NA | Down-regulated − 5.3 | NA |
| Wnt5a | NA | NA | NA | Down-regulated − 13.1 |
| Wnt6 | NA | Up-regulated 2.1 | NA | NA |
| Wnt7B | NA | Up-regulated 2.1 | NA | NA |
| Wnt10a | Up-regulated 2.1 | NA | Down-regulated − 4.1 | NA |