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Sequence alignment of FGFs by subfamily. The sequence alignment employed ClustalX2 (54). Secondary structures are from human FGF-1, rat FGF-7, human FGF-8b, and human FGF-9 crystal structures (39, 42, 43, 55, 56). Labeled lysines and literature reported lysines and arginines are colored in red, and the predicted lysines are colored in blue. The aligned HBSs are highlighted in red.
