TABLE 1.
Nomenclature and structures of chemically modified heparin structures
The letter I stands for iduronate, and A stands for the amino sugar glucosamine.
| Analogue | Predominant repeat | IdoUA-2 | GlcN-6 | GlcN-2 | IdoUA-3 | GlcN-3a |
|---|---|---|---|---|---|---|
| 1 (heparin) | I2SA6SNS | SO3− | 3− | 3− | OH | OH |
| 2 | I2SA6SNAc | SO3− | 3− | COCH3 | OH | OH |
| 3 | I2OHA6SNS | OH | 3− | 3− | OH | OH |
| 4 | I2SA6OHNS | SO3− | OH | 3− | OH | OH |
| 5 | I2OHA6SNAc | OH | 3− | COCH3 | OH | OH |
| 6 | I2SA6OHNAc | SO3− | OH | COCH3 | OH | OH |
| 7 | I2OHA6OHNS | OH | OH | 3− | OH | OH |
| 8 | I2OHA6OHNAc | OH | OH | COCH3 | OH | OH |
| 9 | I2S,3SA6S3S,NS | SO3− | 3− | 3− | 3− | 3− |
a Numbers refer to the ring position of the carbon atoms.