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ErbB ligands expressed in mouse colon
RNA was prepared from flash-frozen whole mouse colon or isolated colon epithelium (n = 4 each) and then subjected to RT-PCR analysis for presence of the indicated ligands (receptor binding specificities indicated in parentheses).
| Ligand | Whole colon | Isolated epithelial cells |
|---|---|---|
| EGF (EGFR) | + | − |
| HB-EGF (EGFR, ErbB4) | + | + |
| Betacellulin (EGFR, ErbB4) | + | − |
| NRG4 (ErbB4) | + | − |
| HRG-1β (ErbB3, ErbB4) | + | − |
| TGF-α (EGFR) | + | + |
