Table 4.
Genotype Distributions and Allele Frequencies in BMI≥25 and BMI<25 Groups
| |
|
BMI≥25 (kg/m2) |
BMI<25 (kg/m2) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| SNP ID | Genotype and allele | T2D, n (%) | Cont, n (%) | p | pa | OR (95% CI) | T2D, n (%) | Cont, n (%) | p | pa | OR (95% CI) |
| rs521674 | AA | 70 (12.9) | 76 (15.6) | 0.30 | — | 68 (13.6) | 68 (12.0) | 0.35 | — | ||
| AT | 255 (47.1) | 209 (43.0) | 228 (45.5) | 242 (42.8) | |||||||
| TT | 216 (40.0) | 201 (41.4) | 205 (40.9) | 256 (45.2) | |||||||
| A | 395 (36.5) | 361 (37.1) | 0.77 | 0.22 | 0.80 | 364 (36.3) | 378 (33.4) | 0.16 | 0.45 | 1.15 | |
| T | 687 (63.5) | 611 (62.9) | (0.57–1.14) | 638 (63.7) | 754 (66.6) | (0.80–1.65) | |||||
| rs553668 | AA | 111 (20.5) | 106 (21.8) | 0.56 | 94 (18.8) | 143 (25.3) | 0.03 | — | |||
| AG | 271 (50.1) | 227 (46.7) | 275 (54.9) | 273 (48.2) | |||||||
| GG | 159 (29.4) | 153 (31.5) | — | 132 (26.3) | 150 (26.5) | ||||||
| A | 493 (45.6) | 439 (45.2) | 0.86 | 0.61 | 0.93 | 463 (46.2) | 559 (49.4) | 0.14 | 0.01 | 0.68 | |
| G | 589 (54.4) | 533 (54.8) | (0.69–1.25) | 539 (53.8) | 573 (50.6) | (0.51–0.92) | |||||
a
Means tests are done with recessive models.