Table 3.

Sphingolipids content in white subcutaneous adipose tissue and epicardial fat tissue in lean non-diabetic, obese non-diabetic, and obese diabetic groups

	Sph	SPA	S1P	C14-Cer	C16-Cer	C18:1-Cer	C18-Cer	C20-Cer	C22-Cer	C24:1-Cer	C24-Cer	Total Cer
SubQ
LND	0.37 ± 0.08	0.05 ± 0.01	0.028 ± 0.003	0.13 ± 0.02	2.9 ± 0.6	0.17 ± 0.02	0.18 ± 0.07	0.32 ± 0.07	1.2 ± 0.14	1.7 ± 0.3	1.2 ± 0.17	7.8 ± 0.8
OND	0.43 ± 0.08	0.11 ± 0.03c	0.027 ± 0.004	0.23 ± 0.06c	3.2 ± 1.1	0.20 ± 0.05a	0.21 ± 0.06	0.35 ± 0.07	1.3 ± 0.18	2.6 ± 0.3c	1.4 ± 0.15a	9.5 ± 0.9c
OD	0.43 ± 0.09	0.11 ± 0.03c	0.078 ± 0.009c,#	0.21 ± 0.04c	5.1 ± 1.3c,#	0.32 ± 0.07c,#	0.31 ± 0.05c,#	0.36 ± 0.11	1.3 ± 0.42	2.4 ± 0.3c	1.4 ± 0.42	11.4 ± 1.2c,#
Epicardial
LND	0.27 ± 0.05	0.06 ± 0.01	0.025 ± 0.002	0.15 ± 0.03	3.7 ± 0.9	0.33 ± 0.08	0.49 ± 0.09	0.32 ± 0.09	0.55 ± 0.09	0.6 ± 0.1	0.5 ± 0.1	6.4 ± 1.1
OND	0.45 ± 0.09c	0.09 ± 0.02c	0.052 ± 0.006c	0.26 ± 0.05c	5.6 ± 0.5c	0.41 ± 0.08a	0.54 ± 0.09	0.33 ± 0.05	0.54 ± 0.08	0.6 ± 0.1	0.6 ± 0.1	8.9 ± 0.4c
OD	0.57 ± 0.11c,*	0.11 ± 0.03c	0.080 ± 0.009c,#	0.33 ± 0.09c,*	5.9 ± 0.8c	0.53 ± 0.08c,#	0.70 ± 0.09c,#	0.33 ± 0.06	0.60 ± 0.07	0.9 ± 0.1c,#	0.6 ± 0.1	9.8 ± 0.8c,^

Values are expressed in pmol/mg tissue (means ± SD)

LND lean non-diabetic, OND obese non-diabetic, OD obese diabetic. SubQ subcutaneous fat tissue

^a p < 0.05, ^b  p < 0.01, ^c  p < 0.001 versus lean non-diabetic, * p < 0.05, ^ p < 0.01, ^#  p < 0.001 versus obese non-diabetic