Table 2.

Sizes and Zeta potentials of diblock polymer:siRNA particles utilized to deliver siRNA to MSCs.

Sample	Charge Ratio	siRNA Concentration	Size (nm)	Zeta Potential (mV)
Polymer:siRNA	1:1	37.5 nM	56.9 ± 13.1	12.2 ± 6.7
Polymer:siRNA	2:1	37.5 nM	59.8 ± 16.1	13.9 ± 9.4
Polymer:siRNA	4:1	37.5 nM	55.6 ± 13.4	10.8 ± 9.8
Polymer:siRNA	8:1	37.5 nM	56.2 ± 15.7	14.8 ± 7.4
Polymer:siRNA	4:1	10 nM	54 ± 12.7	9.6 ± 5.4
Polymer:siRNA	4:1	20 nM	57.2 ± 13.2	11 ± 3.5
Polymer:siRNA	4:1	25 nM	52.7 ± 11.7	14.6 ± 11.1
Polymer:siRNA	4:1	30 nM	56.4 ± 16.7	15.3 ± 9.5
Polymer:siRNA	4:1	37.5 nM	55.6 ± 13.4	13.7 ± 5.4
Polymer only	NA	NA	54.1 ± 11.3	14.2 ± 7.2
DharmaFECT:siRNA	NA	30 nM	159 ± 25.6	11.8 ± 5.2
DharmaFECT:siRNA	NA	37.5 nM	136 ± 18.5	13.8 ± 9.5
DharmaFECT only	NA	NA	24 ± 4.3	13.5 ± 8.3