Table IV.

Mean changes in ASUI scores as a function of changes in percent predicted FEV1 values and ACQ scores

		N (pts.)**	Mean change in ASUI (95% CI)	P value
Changes in percent predicted FEV1
Better (ΔFEV1 ≥ 10%)		213 (163)	0.05 (0.03, 0.07)
Same (−10% ≤ ΔFEV1 <10%)		1657 (384)	0.01 (0.00, 0.01)
Worse (ΔFEV1 ≤−10%)		222 (170)	−0.03 (−0.05, −0.02)	<0.0001
Changes in ACQ* (Δ ACQ)
Better	ΔACQ ≥ −1.5	76 (68)	0.32 (0.28, 0.35)
	−1.0 ≤ ΔACQ < −1.5	111 (100)	0.15 (0.13, 0.18)
	−0.5 ≤ ΔACQ < −1.0	255 (198)	0.09 (0.08, 0.10)
Same	+0.5 > ΔACQ < −0.5	1254 (369)	0.00 (−0.00, 0.01)
Worse	+1.0 > ΔACQ ≥ +0.5	233 (175)	−0.09 (−0.10, −0.07)
	+1.5 > ΔACQ ≥ +1.0	78 (69)	−0.17 (−0.20, −0.14)
	ΔACQ ≥ + 1.5	61 (53)	−0.32 (−0.36, −0.28)	<0.0001

Note: MID for ACQ is 0.5 points

ACQ: Asthma Control Ques ionnaire, ASUI: Asthma Symptom Utility Index, FEV1: Forced expiratoryvolume in the first second

^*ACQ: Better = decrease by ≥ 0.5 points; same = change by <0.5 points; Worse = increase by ≥ 0.5 points.

^**N denotes frequency of events and “pts.” indicates the number of patients