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. 2012 Oct 26;18:2633–2646.

Table 5. Summary of association of myopia with markers on chromosome 15q14 and 15q25 from the literature and the present study.

Locus best SNPs* Gene(s) Study Population best P best OR
15q14
rs634990 rs524952
GOLGA8B ACTC1 GJD2
Solouki et al. [57]
European
2.21×10−14
1.81 (1.42–2.36)#
 
rs634990 rs524952

Hayashi et al. [36]
Japanese
8.781×10−7
 1.32 (1.11–1.56)
 
rs634990
 
Verhoeven et al. [37]**
European Japanese Singapore
9.2×10−23^
1.88 (1.64–2.16)#
 
rs634990
 
 
European
3.87×10−12^
na
 
rs8032019
 

Asian
9.65×10−4^
 na
 
rs634990
 
present study
Han Chinese
1.66×10−6+
1.75 (1.39–2.20)
15q25
rs8027411 rs939658
RASGRF1
Hysi et al. [31]
European
2.07×10−9
1.16 (1.02–1.28)#
 
rs8027411 rs939658

Hayashi et al. [36]
Japanese
0.031
 1.17 (1.03–1.33)
 
rs939661
 
Verhoeven et al. [37]**
European Japanese Singapore
1.22×10−4&
na
  rs8027411 present study Han Chinese 0.17+  0.9 (0.72–1.14)

* not exhaustive; **meta-analysis including results of Hysi et al. and Soluki et al. with others; ^ p<3.56×10–3 considered significant after Bonferroni correction; & p<1.92×10–3 considered significant after Bonferroni correction; # OR for homozygous carriers not available; na not available; +p<0.00066 is considered significant after Bonferroni correction