Skip to main content
. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Placenta. 2012 Jan 21;33(4):278–284. doi: 10.1016/j.placenta.2011.12.019

Table 3.

Comparison of spontaneously occurring placental abruption previously reported in NHP.

References Species n Risk factors for
abruption present
Gestational
age (days or
trimester)
Clinical features Pathology Spontaneous vs.
artificially induced
abruptio placentae
Present study Papio spp. 22 Trauma, multiparity and
humane euthanatia
47–189 Refer to tables 1 and 2 Retro-placental clots Spontaneous
18 Lion-tailed
macaque
1 Multiparity 3rd trimester Maternal weakness, ataxia, pale mucous
membranes, hypothermia and IUFD
10 cm retroplacental blood
clot
Spontaneous
19 Mandrill, Gorilla 2 N/A* Term Stillbirths N/A Spontaneous
20 Gorilla 1 Preeclampsia Term Proteinuria documented in the second half
of the pregnancy, stillbirth
Small placenta,
retroplacental hematomas
Spontaneous
21 Macaca mulata 6 N/A 100–120 IUFD of all 6 fetuses The experimental placental
lobe had a dark brown
color and showed areas of
blood stagnation
Experimental
22, 23 Macaca mulata 7 N/A Near term 2 cases of live births with severe asphyxia
and with secondary brain injury
2 cases of incidental finding of placenta
abruption on routine CS
IUFD, retroplacental clots
and signs of disseminated
intravascular coagulation
Spontaneous
24 Papio spp. 3 Chronic instrumentation
of the fetus
132–142 IUFD , 3 fetuses N/A Complication of the
experimental
procedure
25 Macaca
fascicularis
2 N/A > 140 IUFD , 2 fetuses N/A Spontaneous
*

Not available, IUFD: Intrauterine fetal demise