Figure 5.

Propranolol induces significant alterations in global gene expression of human infantile hemangioma endothelial cells (HemECs). (A) Correlation map comparing the significant gene expression changes (>2 fold gene expression alteration, p<0.05) as determined by microarray analysis between HemECs, human dermal microvascular endothelial cells (HDMVECs), and human coronary artery endothelial cells (HCAECs) treated with sham or 50 μM propranolol for 24 h. (B) RT-PCR confirmation of a subset of genes in HemECs whose expression was statistically altered in the microarray.