Figure 14.

Schematic illustration of the trigeminovascular pathway between the meninges and the cortex. The peripheral limb (meningeal nociceptors) is shown in red. The ascending limb from the spinal trigeminal nucleus (Vc and C1/C2) to the brainstem, thalamus, and hypothalamus is shown in blue. The thalamocortical projections from VPM, PO, and LD/LP are shown in purple, green, and orange, respectively. AH, Anterior hypothalamus; ctg, central tegmental area; LH, lateral hypothalamus; LPO, lateral posterior area; PB, parabrachial area; PH, posterior hypothalamus. For additional abbreviations, see previous figure legends.