Table 1.
Clinicopathologic characteristics of patients included in the study
| Variables | n | % |
|---|---|---|
| Total number of patients | 96 | |
| Age (years) | ||
| Mean ± standard deviation | 65.64 ± 7.23 | |
| <65 | 36 | 37.5 |
| ≥65 | 60 | 62.5 |
| Sex | ||
| Male | 77 | 80.2 |
| Female | 19 | 19.8 |
| Histology | ||
| Adenocarcinoma | 42 | 43.8 |
| Squamous cell carcinoma | 42 | 43.8 |
| Large-cell carcinoma | 8 | 8.3 |
| Undifferentiated carcinoma | 4 | 4.1 |
| Grade | ||
| Low | 25 | 26 |
| Medium/high | 71 | 74 |
| T status | ||
| T1 | 13 | 13.5 |
| T2 | 65 | 67.7 |
| T3 | 18 | 18.8 |
| Regional lymph-node status | ||
| N0 | 50 | 52.1 |
| N1 | 27 | 28.1 |
| N2 | 19 | 19.8 |
| Stage | ||
| I | 41 | 42.7 |
| II | 22 | 22.9 |
| III | 31 | 32.3 |
| IV | 2 | 2.1 |
| Ploidy | ||
| Diploidy | 78 | 81.3 |
| Aneuploidy | 18 | 18.7 |
| Smoking history | ||
| Yes | 81 | 84.4 |
| No | 15 | 15.6 |
| Adjuvant treatment | ||
| Chemotherapy-adjuvant | 72 | 75.0 |
| Radiotherapy-adjuvant | 41 | 42.7 |
| Blood-vessel infiltration | 41 | 42.7 |
| Lymphatic infiltration | 21 | 21.9 |
| High expression of p53 | 55 | 57.3 |
| High expression of caspase-3 | 24 | 25.0 |
| High expression of γ-H2AX | 25 | 26.0 |
| High Ki67 labeling index | 29 | 30.2 |