Table 2. Peaks with low Mann-Whitney U test and low local FDR.
m/z | laser energy | note | ENU mean | ENU sem | Ctl mean | Ctl sem | p value | local FDR |
6909 | med | z = 2 for 13840 | 9.97 | 0.28 | 8.18 | 0.25 | 0.000008 | 0.0014 |
6859 | med | z = 2 for 13725 | 14.07 | 0.61 | 10.61 | 0.43 | 0.000029 | 0.0025 |
22054 | med | z = 3 for 66110 | 1.00 | 0.09 | 0.55 | 0.05 | 0.000038 | 0.0025 |
66110 | high | Albumin | 17.04 | 0.82 | 13.08 | 0.52 | 0.000084 | 0.0054 |
46643 | high | 0.24 | 0.04 | 0.46 | 0.04 | 0.000105 | 0.0054 | |
13725 | med | transthyretin (Cys-) | 74.09 | 2.76 | 58.45 | 2.31 | 0.000131 | 0.0054 |
3493 | low | α1-macroglobulin fragment | 12.17 | 2.28 | 6.51 | 1.66 | 0.000201 | 0.0078 |
27410 | med | dimer of 13725 | 0.59 | 0.03 | 0.45 | 0.03 | 0.000273 | 0.0078 |
22893 | high | PGD2S | 17.94 | 1.09 | 22.97 | 0.84 | 0.000334 | 0.0078 |
21365 | high | 3.39 | 0.17 | 4.20 | 0.13 | 0.000369 | 0.0078 | |
6823 | med | z = 2 for 13670 | 9.85 | 0.40 | 7.61 | 0.37 | 0.000407 | 0.0078 |
33109 | high | z = 2 for 66110 | 5.24 | 0.22 | 4.14 | 0.16 | 0.000407 | 0.0078 |
36781 | high | 0.74 | 0.07 | 1.10 | 0.06 | 0.000449 | 0.0078 | |
14120 | med | 24.90 | 1.19 | 31.01 | 1.57 | 0.000658 | 0.0161 | |
110080 | high | 0.03 | 0.00 | 0.04 | 0.00 | 0.000722 | 0.0161 | |
13670 | med | ? transthyretin (sulfonated) | 49.70 | 1.99 | 38.96 | 2.08 | 0.000792 | 0.0161 |
131938 | high | dimer of 66110 | 0.76 | 0.09 | 0.44 | 0.04 | 0.000868 | 0.0161 |
3504 | low | 2.75 | 0.31 | 1.80 | 0.29 | 0.001041 | 0.0161 | |
38453 | high | 0.65 | 0.04 | 0.83 | 0.03 | 0.001041 | 0.0161 | |
21593 | high | 3.30 | 0.17 | 4.04 | 0.12 | 0.001138 | 0.0161 | |
6795 | med | z = 2 for 13601 | 16.26 | 0.47 | 13.89 | 0.45 | 0.001244 | 0.0161 |
13913 | med | transthyretin (glutathionylated) | 122.75 | 5.28 | 143.62 | 6.35 | 0.001358 | 0.0161 |
27538 | med | 0.81 | 0.03 | 0.68 | 0.03 | 0.001482 | 0.0161 | |
2887 | low | 2.38 | 0.20 | 1.47 | 0.13 | 0.001482 | 0.0161 | |
6865 | low | z = 2 for 13725 | 11.02 | 0.73 | 8.53 | 0.58 | 0.001760 | 0.0478 |
13788 | med | transthyretin (-Cys-Gly) | 51.29 | 1.34 | 44.48 | 1.64 | 0.002265 | 0.0868 |
13601 | med | transthyretin (unmodified) | 80.66 | 2.00 | 70.86 | 2.33 | 0.003398 | 0.1167 |
Peaks in bold type are z = 1. Peaks in italics are aliases (z = 2 or 3, or dimers) of the indicated protein.