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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Mol Cancer Res. 2012 Sep 10;10(11):1462–1472. doi: 10.1158/1541-7786.MCR-12-0335

Figure 4. SUZ12 knockdown triggers apoptosis of human EOC cells.

Figure 4

A, control and shSUZ12 expressing SKOV3 cells were examined for cell cycle distribution by FACS. The percentage of sub-G1 cells was indicated. B, quantitation of A. Mean of three independent experiments with SD. * p<0.001 compared with controls. C, control and indicated shSUZ12-expressing SKOV3 cells were stained for Annexin V, a cell surface marker of apoptosis. Annexin V-positive cells were measured by Guava Nexin assay. The percentage of Annexin V positive cells was indicated. D, quantitation of C. Mean of three independent experiments with SD. * p<0.001 compared with controls. E, same as A and C, but examined for expression of cleaved lamin A, caspase 3 and PARP p85, in control and indicated shEZH2-expressing cells.